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In a very current review, we described the identification and the characterization of a new atypical opioid receptor with exceptional damaging regulatory Houses toward opioid peptides.1 Our results showed that ACKR3/CXCR7, hitherto called an atypical scavenger receptor for chemokines CXCL12 and CXCL11, is also a broad-spectrum scavenger for opioid

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